By W. R. Hess (auth.), Yechiel Becker (eds.)
African swine fever (ASF) is because of a pandemic that's categorised as a member of the Iridovirinae kinfolk. The affliction within the warthog, the traditional host, in Africa was once defined in 1921 via R. E. Montgomery. The reservoir of the vi rus is inti cks. The i ntroduct i on of family pi gs into territory occupied by way of warthogs i nf ected wi th ASF within the 1960's has endangered the pig all over the world. The household pig is very delicate to ASF and develops a devastating sickness that kills the pig with no giving the immune method an opportunity to guard the animal opposed to the virus an infection. the power of ASF virus to contaminate and spoil cells of the reticuloendothelial method leaves a defenseless host that succumbs to infection that may be defined as an bought immune deficiency di sease of family pi gs. creation of the virus into Iberia within the 1960's resulted in a sequence of ASF epidemics in Spain and Portugal . . and later in France, that prompted heavy fiscal losses. among 1976 and 1960, ASF virus made its visual appeal in Malta and Sardinia . . in addition to in Brazil, The Dominican Republic . . Haiti, and later in Cuba. In 1985-6 . . ASF seemed in Belgium and The Netherlands.
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F. Arch. Ges. Virusforsch. 31: 387-389, 1970. M. F. Arch. Ges. Virusforsch. 45: 272-277, 1974. G. C. Immunology~: 75-82, 1982. G. C. Res. Vet. Sci. ~: 75-79, 1983. D. E. Preventive Vet. Med. 2: 53-62, 1984. , Ley, V. and Vifiuela, E. Comm. Eur. Comm. EUR 8466 EN, pp. 254-262, 1982. , Salvador, E. and Ordas, A. Curro Top. Vet. Med. Am. Sci. 22: 214-222, 1982. 6 CHARACTERIZATION OF ASFV PROTEINS ENRIQUE TABARES Departamento de Microbiologia, Facul tad de Medicina, Uni versidad Autonoma de Madrid, Arzobispo Morcillo 4, Madrid 28029, Spain.
More pronounced eosinophilic staining of the periarterial macrophage sheaths and the areas of erythropoiesis. Spleens from pig 12. 13. and 16 DPr had erythropoiesis. The spleen from a 14 DPr pig was normal. 27 Liver. Enlarged Kupffer cells in a 7 DPI liver was the only change associated with ASF infectlon. Tonsils. At 6 and 7 DPI there were a few mitotic figures in the interfollicular areas. Brain. One pig at 6 DPI had a mild lymphoreticular cell infiltrate in the choroid plexus. Two 11 DPI pigs had mild lymphoreticular cell infiltrate in the choroid plexus.
Late RNA transcription is, like early RNA synthesis, host RNA polymerase-II independent, since the synthesis of both takes place in the presence of either a-amanitin or 5,6-dichloro-l, 8, D-ribofuranosylbenzimidazole (J. L. Salas and E. Vifiuela, unpublished data) • A two-dimensional gel electrophoresis analysis of lysates from ASF virus-infected cells, pulse-labeled with 35S-methionine at different times of infection, has demonstrated 81 acid and 14 basic virus-induced polypeptides, whose molecular weight values range from 220 to 10 K.